Sialylated HMO Branch
3'-SL adds a sialylated structure to a portfolio that may already contain fucosylated and neutral HMOs. It is useful when the nutrition company wants a complete HMO-family story.
Sialylated HMO
3'-Sialyllactose Sodium Salt (3'-SL)
3'-Sialyllactose Sodium Salt gives technical teams a sialylated HMO option for advanced nutrition projects. Nutrition companies often review it with 6'-SL when they want a broader sialylated portfolio or a more complete HMO family range.
Nutrition companies usually review assay basis, sodium contribution, impurity profile, moisture, and microbiology before sampling or commercial formulation.
- Sialylated HMO sodium salt for multi-HMO portfolio depth
- Sodium contribution and residue indicators reviewed before sampling
- Heat-stability and release-inspection support for formulation review
Fermentation-Based HMO- Molecular Formula
- C23H38NO19Na
- Relative Molecular Mass
- 655.53
- HMO Family
- Sialylated HMO
- Appearance
- White to off-white powder
CAS No.128596-80-5
MOQ10 kg
Shipping PortShanghai or Qingdao
Purity3'-SL water free, >=88.0%
Application and Regulatory Review
3'-SL Application, Use-Level, and Regulatory Review
Review 3'-SL application direction, use-level references, permitted categories, labelling points, and destination-market requirements before sampling, quotation, or commercial formulation.
Immune-Response R&D Screening
The six-HMO comparison gives 3'-SL a clear R&D angle. We use it for screening and formulation discussion, not for disease prevention or treatment claims.
Specialty Nutrition and FSMP Review
3'-SL can be discussed for specialty nutrition projects where the target population, dosage, sodium contribution, and document requirements need careful review.
Pairing with 6'-SL
3'-SL pairs naturally with 6'-SL when nutrition companies want sialylated HMO coverage or a multi-HMO blend with acidic HMO components.
EU Novel Food Review
EU 2021/96 authorises 3'-SL sodium salt as a novel food, and EU 2024/1047 gives a newer source-specific 3'-SL sodium salt authorisation. Nutrition companies should also review same-day-use and age-group labelling requirements.
U.S. GRAS Review
The FDA GRAS Notice Inventory includes 3'-SL sodium salt entries with 'no questions' response letters, including GRN 766, GRN 880, GRN 921, GRN 1015, GRN 1052, GRN 1074, and GRN 1299. GRN 1299 provides a current 2026 reference for formula and young-child foods.
Use-Level Review Notes
- FDA GRN 1299 lists 3'-SL sodium salt for non-exempt infant formula for term infants up to 0.28 g/L.
- FDA GRN 1299 lists formula-type drinks for young children up to 0.28 g/L and other drinks for young children up to 0.15 g/L.
- FDA GRN 1299 lists instant cereals for infants and young children up to 1.66 g/kg and other foods for infants and young children up to 1.25 g/kg.
- EU entries for 3'-SL sodium salt show infant formula levels around 0.2 g/L to 0.28 g/L, depending on the authorised source.
- EU follow-on formula entries show around 0.15 g/L to 0.28 g/L in final product ready for use.
- EU food supplement entries include 0.5 g/day to 0.7 g/day, with restrictions for infants and young children.
- Because this product is a sodium salt, include sodium contribution in the formulation review.
Technical Data
Specification Snapshot
3'-SL Specification
| Color | White to off-white |
|---|---|
| Appearance | Powder |
| 3'-Sialyllactose Sodium Salt (Water-Free) | >=88.0% |
| N-Acetylneuraminic Acid | <=1.5% |
| 3'-Sialyllactulose | <=5.0% |
| D-Lactose | <=3.0% |
| Moisture | <=10.5% |
| Sodium | <=4.2 x 10^3 mg/100 g |
| Residual Protein | <=100 mg/kg |
| Endotoxins | <=10 EU/mg |
| Total Arsenic | <=0.1 mg/kg |
| Lead | <=0.05 mg/kg |
| Total Plate Count | <=500 CFU/g |
| Enterobacteriaceae | <10 CFU/g |
| Salmonella | Absent in 25 g |
Specification Notes
- Product Description
- 3'-Sialyllactose Sodium Salt (3'-SL) is a sialylated HMO sodium salt for advanced nutrition formulations that need acidic HMO coverage and sodium contribution review.
- Storage Condition
- Store at room temperature in sealed packaging. Keep dry and away from light.
- Pack Size and Shelf Life
- 20 kg per carton or drum, packed as 10 kg x 2 bags. Shelf life: 24 months.
- Packaging Material
- Inner packaging uses food-grade PE bags and food-grade aluminum foil bags. Outer packaging uses a cardboard drum or carton.
- Anticipated Use
- For formulation review in children's milk powder, infant formula, older-infant and young-child formula, and infant formula for special medical purposes, subject to the destination market's authorization.
Project Support
Planning a 3'-SL or Multi-HMO Project?
Share your specification target, annual forecast, and market requirements. We will help check supply options, sample route, and application direction.