Neutral Core Portfolio Depth
LNT is useful when a nutrition company wants neutral-core coverage beyond LNnT. It helps the brand explain that the HMO system is broader than one fucosylated product and one neutral product.
Neutral Core HMO
Lacto-N-tetraose (LNT)
Lacto-N-tetraose helps nutrition companies expand neutral core HMO coverage in a product range. It is useful when brands want to compare neutral HMO structures, build multi-HMO portfolios, or support child-nutrition product development.
Nutrition companies usually review LNT purity, residue indicators, application fit, and document needs together with the commercial supply path.
- Neutral core HMO portfolio fit for advanced blends
- Water-phase purification for high purity and cleaner flavor
- Application review backed by batch-level quality control
Fermentation-Based HMO- Molecular Formula
- C26H45NO21
- Relative Molecular Mass
- 707.63
- HMO Family
- Neutral Core HMO
- Appearance
- White to off-white powder
CAS No.14116-68-8
MOQ10 kg
Shipping PortShanghai or Qingdao
PurityLNT water free, >=80.0%
Application and Regulatory Review
LNT Application, Use-Level, and Regulatory Review
Review LNT application direction, use-level references, permitted categories, labelling points, and destination-market requirements before sampling, quotation, or commercial formulation.
Young-Child and Complementary Food Concepts
LNT fits young-child nutrition, milk-based drinks, cereal concepts, purees, and advanced child-nutrition product ideas where the local market allows use.
Synbiotic R&D Direction
Related LNT-series material supports synbiotic discussion with selected probiotic strains. We use this for R&D matching, not as a finished claim.
Blend Planning with All HMO Families
LNT can sit with 2'-FL, 3-FL, LNnT, 3'-SL, and 6'-SL when nutrition companies want fucosylated, neutral core, and sialylated coverage in one concept.
EU Novel Food Review
EU 2020/484 authorises LNT as a novel food, and EU 2026/397 gives a newer source-specific LNT authorisation. These entries show why source, production strain, food category, and data-protection status must be checked before launch.
U.S. GRAS Review
The FDA GRAS Notice Inventory includes LNT entries with 'no questions' response letters, including GRN 833, GRN 923, GRN 1017, GRN 1068, and GRN 1258. GRN 1176 was ceased at the notifier's request, so we do not use it as support.
Use-Level Review Notes
- FDA GRN 1258 lists LNT for non-exempt infant formula for term infants at 0.8 g/L.
- FDA GRN 1258 also lists other food categories at levels up to 20 g/L. Treat those as category-specific GRAS references, not as one universal use level.
- EU LNT entries vary by authorised source. Public entries show infant formula levels from 0.8 g/L to 1.82 g/L in final product ready for use.
- EU follow-on formula entries show 0.6 g/L to 1.82 g/L in final product ready for use, depending on the authorised source.
- EU food supplement entries include 2.0 g/day and 4.6 g/day depending on the entry and population restrictions.
- Before quoting for an EU nutrition company, confirm source, manufacturing route, intended population, and whether any data-protection condition affects the project.
Technical Data
Specification Snapshot
LNT Specification
| Color | White to off-white |
|---|---|
| Appearance | Powder |
| Lacto-N-tetraose (Water-Free) | >=80.0% |
| Lacto-N-triose II | <=5.0% |
| Linear Lacto-N-neohexaose II and Para-LNnH II | <=5.0% |
| D-Lactose | <=5.0% |
| D-Galactose and D-Glucose | <=5.0% |
| Other Carbohydrates | <=15.0% |
| Moisture | <=9.0% |
| Ash | <=1.0% |
| Residual Protein | <=100 mg/kg |
| Endotoxins | <=10 EU/mg |
| Total Arsenic | <=0.2 mg/kg |
| Lead | <=0.05 mg/kg |
| Total Plate Count | <=500 CFU/g |
| Molds | <=10 CFU/g |
| Yeasts | <=10 CFU/g |
| Enterobacteriaceae | <10 CFU/g |
| Salmonella | Absent in 25 g |
Specification Notes
- Product Description
- Lacto-N-tetraose (LNT) is a neutral core HMO ingredient for multi-HMO formulation work. It gives nutrition companies another neutral structure to review alongside LNnT and fucosylated HMOs.
- Storage Condition
- Store at room temperature in sealed packaging. Keep dry and away from light.
- Pack Size and Shelf Life
- 20 kg per carton or drum, packed as 10 kg x 2 bags. Shelf life: 24 months.
- Packaging Material
- Inner packaging uses food-grade PE bags and food-grade aluminum foil bags. Outer packaging uses a cardboard drum or carton.
- Anticipated Use
- For formulation review in children's milk powder, infant formula, older-infant and young-child formula, and infant formula for special medical purposes, subject to the destination market's authorization.
Project Support
Planning a LNT or Multi-HMO Project?
Share your specification target, annual forecast, and market requirements. We will help check supply options, sample route, and application direction.